genomics
Nucleus's Vitruvian score reports embryo trait ranges, not a guaranteed IQ gain News
Nucleus's whitepaper reports a 14.3-point high-to-low embryo-score spread for ten hypothetical embryos, while medical and advertising bodies say clinical trait-selection claims are unproven or inadequately supported.
DeepMind precomputed every single-letter change in human DNA News
Google DeepMind released AlphaGenome Atlas, a free one-petabyte database giving predicted molecular effects for all 9 billion possible single-letter changes to the human genome, and says it is not approved for any clinical use.
Genome language models: predicting DNA the way a chatbot predicts text Lesson
Genome language models are trained to predict the next base in a DNA sequence, the same objective that produces chatbots, and they turn out to learn enough biology to write working viral genomes from scratch.
gget Tool
An open-source command-line and Python tool for querying genomic databases with exact, deterministic lookups. New benchmark work showed wrapping an AI agent around gget's 'virus' module lifted viral-sequence retrieval accuracy from as low as 17% to above 90% -- a concrete template for pairing models with hard tools.
Nucleus Vitruvian Tool
Nucleus's consumer-facing trait-score release for height, BMI and an intelligence measure; its claims require careful reading and are contested by medical and advertising bodies.
Evo 2 Tool
Arc Institute's open genome language model for DNA, used to design bacteriophage genomes that were synthesized and shown to work in living bacteria; weights and code are public.
AlphaGenome Atlas Tool
Free browsable database of predicted molecular effects for all 9 billion possible single-letter changes to human DNA, with a single impact score per variant. Free for academic and non-commercial use via web portal and API; explicitly not validated for clinical use.
AlphaGenome API client Tool
Google DeepMind's open-source client for querying AlphaGenome variant-effect predictions from Python, for researchers who want programmatic access rather than the web portal.