protein-design
Claude designed protein binders that worked about half the time News
Anthropic gave Claude Mythos 5.1 open-source protein design tools and sent its output to outside labs, where nearly 50 percent of its designs across 12 targets bound successfully -- against the 10 to 15 percent hit rate typical of the field.
De novo protein design: how a computer invents a molecule that sticks Lesson
De novo protein design means inventing a protein that does not exist in nature and that binds a chosen target, by predicting how a chain of amino acids will fold and then searching for a chain that folds into a shape which fits. It works because structure prediction got good enough to grade designs before anyone builds them.
Claude designed protein binders against 14 of 15 targets and two labs built every one of them News
Anthropic said on August 18 that Claude designed minibinders against 15 protein targets and succeeded on 14, with hit rates of 26.7 and 22.6 percent against the 10 to 15 percent typical of protein design campaigns, validated by two independent contract labs.
Virtual Lab Tool
The open-source multi-agent research framework behind the Nature nanobody paper, where an LLM principal investigator coordinates specialist agents over tools like ESM, AlphaFold-Multimer and Rosetta. Runnable on your own project with your own agent roster.
Chai Discovery design suite Tool
An interactive design canvas for biologics rather than a prediction tool: choose an antibody format, choose or infer the target structure, pick the epitope, target a specific antigen state, and specify chemical modifications. Commercial access with limited academic availability.
Adaptyv Bio Tool
A contract lab that will express and measure binding for protein designs you submit, including designs produced by a model. One of the two independent labs that validated Anthropic's Claude-designed binders.